The University of Plymouth invites expressions of interest from suitably qualified and experienced organisations for the supply, installation, commissioning and support of a Time-of-Flight Inductively Coupled Plasma Mass Spectrometer (TOF-ICP-MS) to support frontier environmental and analytical research. The University requires a Time-of-Flight Inductively Coupled Plasma Mass Spectrometer (TOF-ICP-MS) with both single particle and single cell analytical capabilities. The system must achieve limits of detection at parts-per-billion (ppb) concentrations and particle size detection capabilities of approximately 15 nm. The instrument must be capable of simultaneous multi-element and isotopic analysis, enabling the quantification of multiple elements and their isotopes within individual particle or cell events in complex environmental matrices. The equipment will support laboratory-based fundamental and frontier research programmes. The proposed solution must include all ancillary equipment necessary for operation, including a suitable autosampler, desolvation system and specialist software for instrument control, data acquisition and data analysis. The software should support the quantification and reporting of particle mass, particle size and number concentration data. The successful supplier will be required to provide delivery, installation, commissioning and performance verification of the complete system, together with comprehensive training for a team of PhD-level researchers and technical staff. The University also requires an appropriate warranty package and service and maintenance support for a period of approximately two to three years following installation. Suppliers should note that installation may require coordination with University stakeholders to undertake minor laboratory modifications and infrastructure works prior to commissioning. Respondents are invited to provide details of any facility, utility, environmental or health and safety requirements associated with their proposed solution. This should include any specific operational considerations, hazards or restrictions, such as high-temperature plasma generation, magnetic field exposure, specialist ventilation requirements, or precautions relating to personnel with medical implants, including pacemakers. Generic risk assessment information and technical facility specifications should also be provided. The procurement of this Time-of-Flight Inductively Coupled Plasma Mass Spectrometer (TOF-ICP-MS) is subject to the successful award of funding through a UKRI Research Infrastructure Renewal Fund bid. Any subsequent procurement activity and contract award will be conditional upon confirmation of funding.