The University of Edinburgh is seeking to award KR Analytical Ltd the contract for the purchase of a MassTech Atmospheric Pressure Matrix Assisted Laser Desorption Ionisation Ultra High Resolution Source (AP-MALDI UHR).

The MassTech AP-MALDI UHR is required to provide high-resolution tissue-imaging capability (5–20 µm) on the University's existing Thermo Scientific Orbitrap Exploris 240 and Orbitrap Stellar mass spectrometers. It is the only source identified as compatible with the existing instruments' ion interfaces, acquisition controls and operating software, enabling seamless integration with established workflows. The system provides the specialist functionality required for molecular tissue imaging, including controlled tissue scanning, a small laser spot, optical sample observation and synchronised data acquisition to facilitate the reconstruction of molecular images. Its interchangeable design also allows the Exploris 240 to retain its existing LC-MS functionality when the MALDI source is not in use. No alternative solution has been identified that meets the combined technical, compatibility and integration requirements of the proposed application. The MassTech AP-MALDI UHR is therefore considered the only currently identified solution capable of meeting the University's immediate requirements.